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Semaglutide

Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist originally developed for type 2 diabetes. It has since become one of the most clinically studied peptides for weight management, marketed as Ozempic and Wegovy.

Quick facts

Half-life
~7 days
Administration
Subcutaneous injection (weekly)
Primary use
Weight management, blood sugar regulation

How it works

Semaglutide mimics the GLP-1 hormone, which is released after eating. It slows gastric emptying, reduces appetite by acting on the brain's satiety centres, and stimulates insulin secretion in a glucose-dependent manner.

Reported benefits

  • Significant and sustained weight reduction
  • Improved blood glucose control
  • Reduced cardiovascular risk in diabetic patients
  • Appetite suppression and reduced food cravings

Typical dosing protocol

Dosing

Starting at 0.25 mg/week, titrating up to 1–2.4 mg/week over several months

Cycle length

Long-term / ongoing under medical supervision

Dosing information is for educational reference only. Individual needs vary. Always consult a healthcare professional.

Safety & considerations

Approved for medical use in the UK under prescription. Common side effects include nausea, vomiting, and diarrhoea. Must only be used under medical supervision.

Tags

fat-lossweightGLP-1diabetesappetite
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Important: All content is for informational purposes only. Not medical advice. Always consult a qualified healthcare professional before starting any peptide protocol.