GHRP-6
GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide that stimulates growth hormone secretion via the ghrelin receptor. It is one of the original GH secretagogue peptides and is notable for its significant appetite-stimulating effect.
Quick facts
- Half-life
- ~15–60 minutes
- Administration
- Subcutaneous injection
- Primary use
- Growth hormone release, appetite stimulation
How it works
GHRP-6 binds to the GHS-R1a (ghrelin) receptor in the pituitary gland and hypothalamus, triggering a strong pulse of growth hormone release. It also stimulates hunger through ghrelin pathway activation — a key distinction from the more selective Ipamorelin.
Reported benefits
- Strong growth hormone pulse stimulation
- Increased muscle mass and reduced body fat over time
- Significant appetite stimulation — useful in a caloric surplus
- Improved recovery and sleep quality
Typical dosing protocol
Dosing
100–300 mcg per injection, 2–3x daily on an empty stomach
Cycle length
8–12 weeks
Dosing information is for educational reference only. Individual needs vary. Always consult a healthcare professional.
Safety & considerations
May cause significant hunger, water retention, and elevated cortisol and prolactin — unlike Ipamorelin. Not approved for human use in the UK. Consult a healthcare professional before use.
Tags
Important: All content is for informational purposes only. Not medical advice. Always consult a qualified healthcare professional before starting any peptide protocol.